There are strong electromagnetism interruption in the process of high power electron beam parameters measure and diagnosis. The Charge Coupled Devices(CCD) is irradiated by strong electron pulse，laser and X-ray. According to the analysis on the CCD imaging principle and the measure on high energy particles，the changes of the CCD output signals under the radiation environment are monitored as well as the CCD imaging after the experiment. The soft-damage and hard-damage of CCD are discussed. It is found that the damage occurs at the grid electrode of the device instead of at the light activated elements. The response characteristics of beam whose energy reaches the damage threshold are obtained. The evaluation on radiation damage is given, which ensures the reliability of beam parameters measure of accelerator.