In modern wars, the concealment of communication between aircrafts is the key factor for aircraft to complete the combat, reconnaissance and other tasks. How to improve the anti-interception performance of the system becomes the key problem of the military communication system design. The application of the theory of Low Probability of Interception(LPI) system in communication waveform design is studied. The anti-interception performance of communication waveform is measured by intercepting distance and the LPI quality factor. The factors that affect the anti-interception performance of the system and the methods to improve it are analyzed. On this basis, the effects of different modulation and demodulation modes, channel coding modes and frequency hopping parameters on the anti-interception performance of communication systems are investigated. The simulation model of anti-interception communication system is established, and the interception distance, quality factor and error bit rate of the system are simulated. Finally, a communication system with interception distance less than communication distance is obtained. The validity of the method is verified, and it provides a reference for the design of LPI system.