In view of the different cleaning frequency ranges required by different cleaning materials in the industry, the ultrasonic transducers that need to be connected are also different. In order to improve the adaptability of the ultrasonic generator to transducers of different frequency ranges, this paper designs a closed-loop control system for frequency reference and frequency-locked loop circuit tracking by the upper monitor. The whole system generates Pulse Width Modulation(PWM) pulse signals by STM32 main controller. It controls the EXB841 optimized driving circuit, driving high frequency full bridge invert circuit, and ensuring the maximum output power of the transducer through impedance matching and output current detection. At the same time, for different frequency ranges of ultrasonic transducers, it is necessary to adjust the given input and keep the generator in a certain range of base-value for frequency tracking. The working frequency of the ultrasonic transducer test prototype is 28.8 kHz and the maximum power is 1 500 W. The resonant frequency of the system is kept around 28.8 kHz after the system is connected, and the output power is approximately the maximum. The test results show that the system has good adaptability to the ultrasonic transducer whose working frequency is 20-40 kHz.