Some algorithms in the Virtual-Multi-Input Multi-Output(V-MIMO) system by an antenna launching multiplexing data are introduced, such as channel estimation, signal detection method and the optimal weights of search algorithm. Firstly, the Least Mean Square(LMS) algorithm is applied to two channel estimation in V-MIMO system, to prevent the channel estimation error caused by the weakness in the data channel during a frame time, guaranteeing the accuracy of channel estimation. Secondly, V-MIMO system utilizes the Maximum Likelihood(ML) detection algorithm to improve the detection accuracy and reduce the bit error rate. Finally, the traversal algorithm and variable step breaklocal algorithm are adopted respectively for less users and more users data transmission to search the optimal weights, which reduce the computational complexity of the system in 2×2,1×2,2×3,2×4 of the actual test, V-MIMO system improve the transmission efficiency of at least 70% on the basis of invariable power and bandwidth, and reduce the number of the transmitting antenna.