Aiming at studying the bioelectromagnetism problem of using antenna as a radio frequency radiation source, by using 3-dimensional electromagnetic simulation software(High Frequency Structure Simulator, HFSS) based on Finite Element Method(FEM), the model of influence on human head exposuring to the radiation caused by the mobile antenna, and cab’s driver occupational electromagnetic exposure model of subway are simulated. The influence of the settings of radiation boundary condition and Perfect Matching Layers(PML) on the accuracy of the simulation results in electric small size model and electric large size model is analyzed. Comparing with existed literature's simulation results of time domain finite difference method, the reliability of perfect matching layers with thickness of λ/2 as the boundary condition is verified. Combining the accuracy of the simulation results, the number of grid segmentation and the speed of calculation, it is indicated that the antenna near-field radiation problem of electric small size model should choose the second-order basis function for grid mesh, and electric large size model should choose the mixed basis function for grid mesh.